The U.S. Department of Energy (DOE) has announced new collaboration agreements with 24 organizations to advance the Genesis Mission, a national initiative aimed at using artificial intelligence (AI) to accelerate scientific discovery, enhance national security, and promote energy innovation.
This announcement follows President Trump’s Executive Order on Removing Barriers to American Leadership in Artificial Intelligence and is part of the America’s AI Action Plan released earlier this year. The plan seeks to encourage innovation, reduce reliance on foreign sources, and strengthen the country’s scientific capabilities.
A White House meeting held today brought together industry representatives, Secretary of Energy Chris Wright, DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil, and Michael Kratsios, Director of the White House Office of Science and Technology Policy. The meeting marked the start of public-private partnerships focused on developing scalable AI infrastructure for scientific research.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
“Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation,” said DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil. “These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The 24 organizations that have signed memorandums of understanding with DOE include technology companies such as Accenture; AMD; Anthropic; Armada; Amazon Web Services; Cerebras; CoreWeave; Dell; DrivenData; Google; Groq; Hewlett Packard Enterprise; IBM; Intel; Microsoft; NVIDIA; OpenAI; Oracle; Periodic Labs; Palantir; Project Prometheus; Radical AI; xAI; and XPRIZE.
These groups responded either through a request for information or have ongoing projects with DOE or its National Laboratories related to activities under the Genesis Mission. Any products developed through these collaborations are intended to be architecture-agnostic.
DOE plans further engagement with private sector partners as well as academic institutions and philanthropic organizations in order to broaden participation in future stages of the mission. Submissions remain open for two requests for information: “Partnerships for Transformational Artificial Intelligence Models” until January 14, 2026 (details at www.genesis.energy.gov), and “Transformational AI Capabilities for National Security” until January 23, 2026.
For more information about partnership opportunities related to this initiative or updates on its progress visit www.genesis.energy.gov or contact genesismission-partnerships@hq.doe.gov.
