Johnson & Johnson has announced plans to invest more than $1 billion in a new advanced cell therapy manufacturing facility in Lower Gwynedd, Montgomery County, Pennsylvania. The project is expected to create 4,000 construction jobs and 500 skilled biomanufacturing positions once the site becomes fully operational.
The facility will expand Johnson & Johnson’s U.S. manufacturing capacity for its pipeline of medicines targeting cancer, immune-mediated, and neurological diseases. The location is about 60 miles from the company’s headquarters in New Brunswick.
“For 140 years, Johnson & Johnson has been a leading innovator in American healthcare, and we are honored to continue advancing that legacy in Pennsylvania,” said Joaquin Duato, Chairman and CEO of Johnson & Johnson. “By uniting scientific excellence with state-of-the-art manufacturing and strategic investment, and by working collaboratively with our communities, we are delivering for patients and creating significant opportunities for workers and families.”
This initiative is part of the company’s previously announced $55 billion investment in U.S. manufacturing, research and development, and technology through early 2029. Much of this investment focuses on North Carolina and Pennsylvania as part of a broader domestic manufacturing strategy.
Currently, Johnson & Johnson operates ten facilities in Pennsylvania with an estimated annual economic impact of about $10 billion. These sites cover more than two million square feet dedicated to manufacturing, research, distribution, and office functions.
“Pennsylvania is a powerhouse for innovation and manufacturing in the life sciences,” said Governor Josh Shapiro. “Just a few years ago we weren’t even on the field – but today we’re competing and winning. We’ve done it by creating the first economic development plan for Pennsylvania in two decades, and following through on it by cutting red tape, making strategic investments in key industries like the life sciences, and strengthening our workforce.”
Shapiro added that companies such as Johnson & Johnson are choosing to increase their investments in Pennsylvania because they see value in the state’s strategy, workforce strength, and efficiency.
The project will receive support from a $41.5 million investment from the Commonwealth of Pennsylvania. According to statements from Governor Shapiro and Department of Community & Economic Development (DCED) Secretary Rick Siger, this includes up to $12 million in tax credits through the Qualified Manufacturing Innovation and Reinvestment Deduction program; up to $2 million via the Manufacturing Tax Credit program; a $15 million grant through PA SITES; and a $10 million Pennsylvania First grant.
Additionally, up to $2.5 million from the Redevelopment Assistance Capital Program will be provided to local community colleges or technical schools to develop workforce training programs supporting talent needs at the new facility.
Johnson & Johnson will also benefit from assistance via Pennsylvania’s Office of Transformation and Opportunity (OTO) under the PA Permit Fast Track Program. The OTO was established by executive order signed by Governor Shapiro in 2024.
The New Jersey Business and Industry Association serves as one of the largest statewide employer organizations nationally—representing private-sector employers across various sectors—and offers advocacy as well as resources designed to enhance business prosperity while facilitating partnerships among businesses, government entities, and academic institutions according to its official website.


